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Thin Layer Chromatography (TLC) Silica Gel is a high-purity, powdery white adsorbent. Its core application is as the stationary phase in Thin Layer Chromatography (TLC) for the qualitative analysis, quantitative analysis, and separation/purification of organic substances. It is widely used in various fields including pharmaceuticals, food, chemicals, and environmental monitoring.
Main Applications by Category
1. Pharmaceutical and Pesticide Analysis
Drug Component Identification: Used for purity testing, impurity monitoring of active pharmaceutical ingredients (APIs), intermediates, and finished products, as well as TLC fingerprint analysis of traditional Chinese medicine. It is a standard method included in pharmacopoeias.Pesticide Residue Detection: Rapid screening of pesticide residues in food and environmental samples.
2. Natural Products and Herbal Medicine
Separation and Purification of Active Components: Used for the separation, purification, and identification of active constituents from herbal medicines and plant extracts.Chemical Synthesis Monitoring: Tracking the progress of organic synthesis reactions and determining product formation and purity.
3. Food and Chemical Industry.
Food Testing: Analysis of trace impurities, additives, and nutritional components in food.Petrochemical Industry: Used for refining petroleum products (removing aromatic hydrocarbons) and as a catalyst carrier.Fine Chemicals: Analysis of main components or trace impurities in organic chemical products.
4. Other Specialized Fields
Life Sciences: Separation and analysis of biomolecules such as amino acids, nucleotides, and lipids.Environmental Monitoring: Analysis of organic pollutants in water and soil.Forensic Analysis: Rapid screening of toxins and drugs.
5. Product Forms and Types
Raw Material Form: TLC silica gel powder can be directly used to coat (spread) silica gel plates or as a carrier for dry cleaning agents (Type H).Pre-coated Plate Form: Common products are pre-made TLC silica gel plates (with glass or aluminum foil backing), categorized into different types by function:Silica Gel G: Contains calcium sulfate hemihydrate (gypsum) as a binder.Silica Gel H: Contains no binder.Silica Gel GF254 / HF254: Contains a fluorescent indicator, allowing observation of fluorescent spots under 254nm UV light.